Hypothyroidism and Thyroid Substitution: Historical Aspects

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Hypothyroidism and Thyroid Substitution: Historical Aspects

The last part of the 19th century was a period of great achievements in medicine and endocrinology. The thyroid gland evolved from being considered a rudimentary structure to an organ related to specific diseases. The singular importance of iodine became acknowledged. Graves-Basedow's disease was described. Surgical treatment evolved with extraordinary speed. Theodor Kocher observed that the cl...

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Congenital hypothyroidism (CH) is a condition of thyroid hormone deficiency present at birth and can result in severe neurodevelopmental impairment, growth failure and permanent mental retardation if treatment is delayed for several months after birth (1-3). Girls are more frequently affected than boys (female to male ratios ranging from 2:1 to 4:1)(4). The mental retardation and neurodevelopme...

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ژورنال

عنوان ژورنال: Journal of Thyroid Research

سال: 2011

ISSN: 2042-0072

DOI: 10.4061/2011/809341